Menopause and hormone replacement therapy

  • Health economics on the menopause
  • Cost utility analysis of hormone replacement therapy (HRT)
  • Observational study of HRT
  • Cognitive debriefing of a women’s health screening tool
  • Consultancy on FDA documents on the menopause
  • Psychometric validation of the SAM/WSM using PNS validation study data
  • Literature review of HRT outcomes in the menopause
  • Development of a conceptual model for vasomotor symptoms in post-menopausal women
  • Trial of two drugs used to treat menopausal symptoms
  • Pilot testing of a paper hot flash diary and questionnaire on the menopause
  • Development of a PRO instrument for measuring mood swings and sleep problems resulting from vasomotor symptoms during the menopause
  • Development of a briefing document for measuring the impact of menopausal hot flushes
  • Development of a PRO for breast pain/pressure and vaginal bleeding/spotting for female patients on HRT
  • Manuscript reporting results of qualitative work to support development of a breast pain daily diary (BP-DD) and vaginal bleeding/spotting daily diary (VBS-DD)