Mapi Values - Experience/Publications

Publications

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Experience

Mapi Values has worked in all major therapeutic areas. Detailed information on our experience in other therapeutic areas will be included when our website is next updated – our experience in oncology is outlined below.

Oncology
Lung cancer

International economic evaluation of new treatment in non-small cell lung cancer in the UK, the Netherlands and Germany and preparation of submission for the Netherlands
Meta-analysis of published data in stage IIIb & IV non-small cell lung cancer
Publication on meta-analysis in non-small cell lung cancer
Poster comparing new treatment with best supportive care in non-small cell lung cancer
Literature review of outcomes and costs during treatment for advanced non-small cell lung cancer
Markov model for monotherapy in non-small cell lung cancer
Selection of patient-reported outcome instrument for use in small cell lung cancer trials
Analysis of health-related quality of life data from clinical trial in non-small cell lung cancer
Literature review to identify utility measure for use in lung cancer patients
Recommendations on assessing health-related quality of life in lung cancer

Breast Cancer

Review of treatment patterns for breast cancer screening, diagnosis and treatment
International economic modeling and submissions of hormonal therapy in postmenopausal advanced breast cancer (UK, Spain, Belgium and the Netherlands)
Development of analysis plan for patient-reported outcome data in breast cancer
Literature review of patient-reported outcome instruments for breast cancer
Development of symptom and health-related quality of life measures for metastatic breast cancer
Systematic review of adjuvant and neoadjuvant treatments in breast cancer
Analysis of patient-reported outcome data from clinical trial in breast cancer
Modeling of treatment adherence in hormonal treatment of advanced breast cancer
Development of perceived tolerability questionnaire in 1st line treatment of advanced breast cancer

Colorectal cancer

International development and validation of patient satisfaction questionnaire in colorectal cancer
Literature review and recommendations for patient-reported outcome assessment in clinical trial of advanced metastatic colorectal cancer
Analysis of patient-reported outcome assessment of treatment in advanced colorectal cancer
Patient and clinician interviews to establish patient-reported outcome issues in colorectal cancer
Conjoint analysis to ascertain patient preferences in colorectal cancer treatment
Publication on the economic impact of a new treatment for metastatic colorectal cancer
Development of cost arguments and brochure for continuous infusion pump for colorectal cancer treatment

Head and neck cancer

International Markov model in head and neck cancer for USA and UK
Submission to SMC for head and neck cancer
Budget impact model for head and neck cancer for UK

Cervical cancer

Markov model in cervical cancer screening
Markov model in human papilloma virus vaccination to prevent cervical cancer
Budget impact model in human papilloma virus vaccination to prevent cervical cancer
Value pack preparation in human papilloma virus vaccination to prevent cervical cancer
Development of patient-reported outcome strategy in human papilloma virus vaccination to prevent cervical cancer
Literature review of patient-reported outcome instruments for use in cervical cancer

Prostate cancer

Development of symptom and health-related quality of life measures in prostate cancer
Strategy and selection of health-related quality of life module in prostate cancer
Development of health-related quality of life module for prostate cancer
Building an interactive model for treatment of late stage prostate cancer
Analysis of health-related quality of life data from clinical trial in prostate cancer
Literature review of health-related quality of life in prostate cancer

Myeloma

Analysis and reporting of patient-reported outcome data from a number of studies and clinical trials in multiple myeloma
Publication on health-related quality of life in myeloma
Presentation on patient-reported outcomes in multiple myeloma
Validation study for patient utilities in multiple myeloma

Leukemia

Assessment of leukemia patients satisfaction with chemotherapy
Utility assessment in elderly acute myelogenous leukemia patients
Position paper on health-related quality of life in elderly acute myelogenous leukemia patients

Various

Development and validation of patient satisfaction questionnaire in chemotherapy treatment
Publication on development and validation of chemotherapy satisfaction questionnaire
Literature review on resource use in basal cell carcinoma
Development of cost model for basal cell carcinoma
Literature review on resource use in cervical intraepithelial neoplasia
Development of cost model for cervical intraepithelial neoplasia
Analysis and reporting of health-related quality of life data in clinical trial in ovarian cancer
Development and validation of measure of impact of symptomatic malignant ascites

Supportive treatment in cancer, and pathologies associated with cancer treatment

Assessment of cancer patients’ satisfaction with anemia treatment and management
Generation of economic evidence for erythropoietin use in cancer
Development of economic model for erythropoietin use in cancer
Linking of cost-utility model with a budget impact model for erythropoietin use in cancer
Consultancy on value dossier to support product used to treat chemotherapy-induced neutropenia
Pilot study of questionnaire administration to patients with chemotherapy-induced neutropenia
Review of questionnaires available to assess the impact of cancer pain
Development of core economic model with adaptations for treatment of invasive aspergillosis (US, UK, NL)
Cost-effectiveness and hospital budget impact analysis of treatment of invasive aspergillosis in Germany
Economic evaluation of empiric treatment of fungal infections in the UK and Italy
Economic evaluation of prophylaxis of fungal infections in neutropenic patients and allergenic HSCT patients in the UK and Netherlands.
Economic evaluation of prevention of skeletal related events in bone metastasis patients suffering of advanced breast cancer

General consultancy in oncology

Advise on selection and implementation of patient-reported outcomes assessment in clinical development of new compounds in oncology
Advise on the assessment of patient-reported outcomes in non-hormonal biological treatments: establishing a marketing strategy
Numerous consulting projects on the assessment of patient-reported outcomes in cancer